Cyclooxygenase-2 Pathway Correlates with VEGF Expression in Head and Neck Cancer. Implications for Tumor Angiogenesis and Metastasis

We evaluated the role of COX-2 pathway in 35 head and neck cancers (HNCs) by analyzing COX-2 expression and prostaglandin E(2) (PGE(2)) production in relation to tumor angiogenesis and lymph node metastasis. COX-2 activity was also correlated to vascular endothelial growth factor (VEGF) mRNA and pro...

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Main Authors: Gallo, Oreste, Franchi, Alessandro, Magnelli, Lucia, Sardi, Iacopo, Vannacci, Alfredo, Boddi, Vieri, Chiarugi, Vincenzo, Masini, Emanuela
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2001
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1505025/
https://ncbi.nlm.nih.gov/pubmed/11326316
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