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High Cell Sensitivity to Helicobacter pylori VacA Toxin Depends on a GPI-anchored Protein and is not Blocked by Inhibition of the Clathrin-mediated Pathway of Endocytosis

Helicobacter pylori vacuolating toxin (VacA) causes vacuolation in a variety of cultured cell lines, sensitivity to VacA differing greatly, however, among the different cell types. We found that the high sensitivity of HEp-2 cells to VacA was impaired by treating the cells with phosphatidylinositol-...

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Udgivet i:Mol Biol Cell
Principais autores: Ricci, Vittorio, Galmiche, Antoine, Doye, Anne, Necchi, Vittorio, Solcia, Enrico, Boquet, Patrice
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2000
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15045/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11071915/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.11.3897
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