Escherichia coli Cytotoxic Necrotizing Factor 1 Effaces Microvilli and Decreases Transmigration of Polymorphonuclear Leukocytes in Intestinal T84 Epithelial Cell Monolayers

Cytotoxic necrotizing factor type 1 (CNF1), a 110-kDa toxin-like protein from pathogenic Escherichia coli strains, induces an actin cytoskeleton reorganization consisting of the formation of prominent stress fibers by permanent activation of the small GTP-binding protein Rho. Since p21Rho regulates...

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Autors principals: Hofman, Paul, Flatau, Gilles, Selva, Eric, Gauthier, Michel, Le Negrate, Gaëlle, Fiorentini, Carla, Rossi, Bernard, Boquet, Patrice
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
Matèries:
Molecular and Cellular Pathogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC108229/
https://ncbi.nlm.nih.gov/pubmed/9596707
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