Escherichia coli Cytotoxic Necrotizing Factor 1 Effaces Microvilli and Decreases Transmigration of Polymorphonuclear Leukocytes in Intestinal T84 Epithelial Cell Monolayers

Cytotoxic necrotizing factor type 1 (CNF1), a 110-kDa toxin-like protein from pathogenic Escherichia coli strains, induces an actin cytoskeleton reorganization consisting of the formation of prominent stress fibers by permanent activation of the small GTP-binding protein Rho. Since p21Rho regulates...

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Pubblicato in:	Infect Immun
Autori principali:	Hofman, Paul, Flatau, Gilles, Selva, Eric, Gauthier, Michel, Le Negrate, Gaëlle, Fiorentini, Carla, Rossi, Bernard, Boquet, Patrice
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Molecular and Cellular Pathogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108229/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9596707/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.6.2494-2500.1998
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