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Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12

IL-12 is considered a critical proinflammatory cytokine for autoimmune diseases such as multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). IL-12 is a heterodimer composed of a p35 subunit and a common p40 subunit shared by other cytokines. Both IL-12 p40(–/–) a...

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Detalhes bibliográficos
Main Authors: Becher, Burkhard, Durell, Brigit G., Noelle, Randolph J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150420/
https://ncbi.nlm.nih.gov/pubmed/12189243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15751
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