HLF/HIF-2α is a key factor in retinopathy of prematurity in association with erythropoietin

An HLF (HIF-1α-like factor)/HIF-2α-knockout mouse is embryonic lethal, preventing investigation of HLF function in adult mice. To investigate the role of HLF in adult pathological angiogenesis, we generated HLF-knockdown (HLF(kd/kd)) mice by inserting a neomycin gene sandwiched between two loxP sequ...

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Main Authors: Morita, Masanobu, Ohneda, Osamu, Yamashita, Toshiharu, Takahashi, Satoru, Suzuki, Norio, Nakajima, Osamu, Kawauchi, Shimako, Ema, Masatsugu, Shibahara, Shigeki, Udono, Tetsuo, Tomita, Koji, Tamai, Makoto, Sogawa, Kazuhiro, Yamamoto, Masayuki, Fujii-Kuriyama, Yoshiaki
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC150350/
https://ncbi.nlm.nih.gov/pubmed/12606578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg117
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