Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

Hypoxia-inducible factor 1 alpha (HIF1alpha) and its related factor, HLF, activate expression of a group of genes such as erythropoietin in response to low oxygen. Transfection analysis using fusion genes of GAL4DBD with various fragments of the two factors delineated two transcription activation do...

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Autores principales: Ema, M, Hirota, K, Mimura, J, Abe, H, Yodoi, J, Sogawa, K, Poellinger, L, Fujii-Kuriyama, Y
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171276/
https://ncbi.nlm.nih.gov/pubmed/10202154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.7.1905
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