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TACE is required for the activation of the EGFR by TGF-α in tumors

The factors and mechanisms that transduce the intracellular signals sent upon activation of the receptor for the epidermal growth factor (EGFR) and related receptors are reasonably well understood and, in fact, are the targets of anti-tumor drugs. In contrast, less is known about the mechanisms impl...

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Bibliografiske detaljer
Main Authors: Borrell-Pagès, Maria, Rojo, Federico, Albanell, Joan, Baselga, Josep, Arribas, Joaquín
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC150344/
https://ncbi.nlm.nih.gov/pubmed/12606576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg111
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