Fibroblast Growth Factor-1 Induced Promatrilysin Expression Through the Activation of Extracellular-regulated Kinases and STAT3

The MMP, matrilysin (MMP-7), has been shown to be overexpressed in prostate cancer cells and to increase prostate cancer cell invasion. Prostate stromal fibroblasts secrete factor(s), including fibroblast growth factor-1 (FGF-1) that induces promatrilysin expression in LNCaP cells. In the present st...

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Bibliographic Details
Main Authors: Udayakumar, Thirupandiyur S, Stratton, Mimi Suzanne, Nagle, Raymond B, Bowden, George Timothy
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2002
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1503316/
https://ncbi.nlm.nih.gov/pubmed/11922392
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