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Polar Transmembrane Domains Target Proteins to the Interior of the Yeast Vacuole

Membrane proteins transported to the yeast vacuole can have two fates. Some reach the outer vacuolar membrane, whereas others enter internal vesicles, which form in late endosomes, and are ultimately degraded. The vacuolar SNAREs Nyv1p and Vam3p avoid this fate by using the AP-3–dependent pathway, w...

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Autors principals: Reggiori, Fulvio, Black, Michael W., Pelham, Hugh R. B.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC15033/
https://ncbi.nlm.nih.gov/pubmed/11071903
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