Extracellular Acidification Alters Lysosomal Trafficking in Human Breast Cancer Cells

Cancer cells invade by secreting degradative enzymes, which are sequestered in lysosomal vesicles. In this study, the impact of an acidic extracellular environment on lysosome size, number, and distance from the nucleus in human mammary epithelial cells (HMECs) and breast cancer cells of different d...

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Main Authors: Glunde, Kristine, Guggino, Sandra E., Solaiyappan, Meiyappan, Pathak, Arvind P., Ichikawa, Yoshitaka, Bhujwalla, Zaver M.
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press Inc. 2003
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502575/
https://ncbi.nlm.nih.gov/pubmed/14965446
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