Extracellular Acidification Alters Lysosomal Trafficking in Human Breast Cancer Cells

Cancer cells invade by secreting degradative enzymes, which are sequestered in lysosomal vesicles. In this study, the impact of an acidic extracellular environment on lysosome size, number, and distance from the nucleus in human mammary epithelial cells (HMECs) and breast cancer cells of different d...

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Autores principales: Glunde, Kristine, Guggino, Sandra E., Solaiyappan, Meiyappan, Pathak, Arvind P., Ichikawa, Yoshitaka, Bhujwalla, Zaver M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2003
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502575/
https://ncbi.nlm.nih.gov/pubmed/14965446
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