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Modeling the Lac repressor-operator assembly: The influence of DNA looping on Lac repressor conformation

Repression of transcription of the Escherichia coli Lac operon by the Lac repressor (LacR) is accompanied by the simultaneous binding of LacR to two operators and the formation of a DNA loop. A recently developed theory of sequence-dependent DNA elasticity enables one to relate the fine structure of...

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Main Authors: Swigon, David, Coleman, Bernard D., Olson, Wilma K.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502547/
https://ncbi.nlm.nih.gov/pubmed/16785444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603557103
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