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Modeling the Lac repressor-operator assembly: The influence of DNA looping on Lac repressor conformation

Repression of transcription of the Escherichia coli Lac operon by the Lac repressor (LacR) is accompanied by the simultaneous binding of LacR to two operators and the formation of a DNA loop. A recently developed theory of sequence-dependent DNA elasticity enables one to relate the fine structure of...

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Autori principali: Swigon, David, Coleman, Bernard D., Olson, Wilma K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502547/
https://ncbi.nlm.nih.gov/pubmed/16785444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603557103
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