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The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement

Kinetochores remain attached to microtubule (MT) tips during mitosis even as the tips assemble and disassemble under their grip, allowing filament dynamics to produce force and move chromosomes. The specific proteins that mediate tip attachment are uncertain, and the mechanism of MT-dependent force...

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Autori principali: Asbury, Charles L., Gestaut, Daniel R., Powers, Andrew F., Franck, Andrew D., Davis, Trisha N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502546/
https://ncbi.nlm.nih.gov/pubmed/16777964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602249103
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