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A burst of auxilin recruitment determines the onset of clathrin-coated vesicle uncoating

Clathrin-coated pits assemble on a membrane and pinch off as coated vesicles. The released vesicles then rapidly lose their clathrin coats in a process mediated by the ATPase Hsc70, recruited by auxilin, a J-domain-containing cofactor. How is the uncoating process regulated? We find that during coat...

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מידע ביבליוגרפי
Main Authors: Massol, Ramiro H., Boll, Werner, Griffin, April M., Kirchhausen, Tomas
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502446/
https://ncbi.nlm.nih.gov/pubmed/16798879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603369103
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