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Structure of the PTEN-like region of auxilin, a detector of clathrin-coated vesicle budding

Auxilin, a J-domain containing protein, recruits the Hsc70 uncoating ATPase to newly budded clathrin-coated vesicles. The timing of auxilin arrival determines that uncoating will commence only after the clathrin lattice has fully assembled and after membrane fission is complete. Auxilin has a region...

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Detalhes bibliográficos
Main Authors: Guan, Rong, Han, Dai, Harrison, Stephen C., Kirchhausen, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955424/
https://ncbi.nlm.nih.gov/pubmed/20826345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.06.016
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