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Contributions of Cell Metabolism and H(+) Diffusion to the Acidic pH of Tumors

The tumor microenvironment is hypoxic and acidic. These conditions have a significant impact on tumor progression and response to therapies. There is strong evidence that tumor hypoxia results from inefficient perfusion due to a chaotic vasculature. Consequently, some tumor regions are well oxygenat...

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Bibliografische gegevens
Hoofdauteurs: Schornack, Paul A, Gillies, Robert J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Neoplasia Press Inc. 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502399/
https://ncbi.nlm.nih.gov/pubmed/12659686
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