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Interaction of two hereditary spastic paraplegia gene products, spastin and atlastin, suggests a common pathway for axonal maintenance
Hereditary spastic paraplegia (HSP) is a neurodegenerative disorder that is characterized by retrograde axonal degeneration that primarily affects long spinal neurons. The disease is clinically heterogeneous, and there are >20 genetic loci identified. Here, we show a physical interaction between...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2006
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1502289/ https://ncbi.nlm.nih.gov/pubmed/16815977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510863103 |
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