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Interaction of two hereditary spastic paraplegia gene products, spastin and atlastin, suggests a common pathway for axonal maintenance

Hereditary spastic paraplegia (HSP) is a neurodegenerative disorder that is characterized by retrograde axonal degeneration that primarily affects long spinal neurons. The disease is clinically heterogeneous, and there are >20 genetic loci identified. Here, we show a physical interaction between...

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Detalhes bibliográficos
Main Authors: Evans, Katia, Keller, Christian, Pavur, Karen, Glasgow, Kristen, Conn, Bryan, Lauring, Brett
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502289/
https://ncbi.nlm.nih.gov/pubmed/16815977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510863103
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