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Tumor-Targeted Hyaluronan Nanoliposomes Increase the Antitumor Activity of Liposomal Doxorubicin in Syngeneic and Human Xenograft Mouse Tumor Models

Naturally occurring high-M(r) hyaluronan, bound to the surface of nanoliposomes (denoted targeted hyaluronan liposomes, or tHA-LIP), is a candidate for active targeting to tumors, many of which overexpress the hyaluronan receptors CD44 and RHAMM. The surfacebound hyaluronan also provides a hydrophil...

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Detalles Bibliográficos
Main Authors: Peer, Dan, Margalit, Rimona
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press Inc. 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502115/
https://ncbi.nlm.nih.gov/pubmed/15256056
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