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Resistance to Platinum-Containing Chemotherapy in Testicular Germ Cell Tumors Is Associated with Downregulation of the Protein Kinase SRPK1

Male germ cell tumors (GCTs) are extremely sensitive to platinum-containing chemotherapy, with only 10% of patients showing therapy resistance. However, the biological basis of the high curability of disseminated GCTs by chemotherapy is still unknown. Recently, we demonstrated that the mammalian ser...

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Detalhes bibliográficos
Main Authors: Schenk, Paul W., Stoop, Hans, Bokemeyer, Carsten, Mayer, Frank, Stoter, Gerrit, Oosterhuis, J. Wolter, Wiemer, Erik, Looijenga, Leendert H. J., Nooter, Kees
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502111/
https://ncbi.nlm.nih.gov/pubmed/15256051
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