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Aberrant Methylation of the Maspin Promoter Is an Early Event in Human Breast Cancer

The maspin gene functions as a tumor suppressor in human breasts, and its expression is frequently lost during breast cancer progression. In vitro models of human breast cancer indicate that the loss of maspin expression is closely linked to aberrant methylation of the maspin promoter. We conducted...

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Detalhes bibliográficos
Main Authors: Futscher, Bernard W., O'Meara, Megan M., Kim, Christina J., Rennels, Margaret A., Lu, Di, Gruman, Lynn M., Seftor, Richard E. B., Hendrix, Mary J. C., Domann, Frederick E.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502109/
https://ncbi.nlm.nih.gov/pubmed/15256060
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