An Estrogen Receptor-α/p300 Complex Activates the BRCA-1 Promoter at an AP-1 Site That Binds Jun/Fos Transcription Factors: Repressive Effects of p53 on BRCA-1 Transcription

One of the puzzles in cancer predisposition is that women carrying BRCA-1 mutations preferentially develop tumors in epithelial tissues of the breast and ovary. Moreover, sporadic breast tumors contain lower levels of BRCA-1 in the absence of mutations in the BRCA-1 gene. The problem of tissue speci...

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Hlavní autoři: Jeffy, Brandon D, Hockings, Jennifer K, Kemp, Michael Q, Morgan, Sherif S, Hager, Jill A, Beliakoff, Jason, Whitesell, Luke J, Bowden, G. Timothy, Romagnolo, Donato F
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2005
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501940/
https://ncbi.nlm.nih.gov/pubmed/16229810
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