Differential Regulation of Cyclooxygenase-2 in Nontransformed and Ras-Transformed Intestinal Epithelial Cells

To determine signaling pathways responsible for modulation of COX-2 expression in nontransformed and transformed epithelial cells, we studied a rat intestinal epithelial (RIE) cell line expressing constitutively active Ras and RhoA. Expression of COX-2 protein was higher in RIE-RhoA(63L) (four-fold)...

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Autores principales: Du, Jianguo, Jiang, Bo, Barnard, John
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2005
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501890/
https://ncbi.nlm.nih.gov/pubmed/16207478
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