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Posttranscriptional Regulation of Cyclooxygenase-2 in Rat Intestinal Epithelial Cells

Modulation of cyclooxygenase-2 (COX-2) mRNA stability plays an important role in the regulation of its expression by oncogenic Ras. Here, we evaluate COX-2 mRNA stability in response to treatment with two known endogenous promoters of gastrointestinal cancer, the bile acid (chenodeoxycholate; CD) an...

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Main Authors: Zhang, Zhonghua, Sheng, Hongmiao, Shao, Jinyi, Beauchamp, R Daniel, DuBois, Raymond N
Format: Artigo
Jezik:Inglês
Izdano: Nature America, Inc. 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508084/
https://ncbi.nlm.nih.gov/pubmed/11228545
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