Rotational Coupling of the Transmembrane and Kinase Domains of the Neu Receptor Tyrosine Kinase

Ligand binding to receptor tyrosine kinases (RTKs) regulates receptor dimerization and activation of the kinase domain. To examine the role of the transmembrane domain in regulation of RTK activation, we have exploited a simplified transmembrane motif, [VVVEVVV](n), previously shown to activate the...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Bell, Charlotte A., Tynan, John A., Hart, Kristen C., Meyer, April N., Robertson, Scott C., Donoghue, Daniel J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2000
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15017/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11029057/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.10.3589
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