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Toxoplasma gondii scavenges host-derived lipoic acid despite its de novo synthesis in the apicoplast
In contrast to other eukaryotes, which manufacture lipoic acid, an essential cofactor for several vital dehydrogenase complexes, within the mitochondrion, we show that the plastid (apicoplast) of the obligate intracellular protozoan parasite Toxoplasma gondii is the only site of de novo lipoate synt...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1500979/ https://ncbi.nlm.nih.gov/pubmed/16778769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601189 |
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