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Toxoplasma gondii scavenges host-derived lipoic acid despite its de novo synthesis in the apicoplast

In contrast to other eukaryotes, which manufacture lipoic acid, an essential cofactor for several vital dehydrogenase complexes, within the mitochondrion, we show that the plastid (apicoplast) of the obligate intracellular protozoan parasite Toxoplasma gondii is the only site of de novo lipoate synt...

詳細記述

保存先:
書誌詳細
主要な著者: Crawford, Michael J, Thomsen-Zieger, Nadine, Ray, Manisha, Schachtner, Joachim, Roos, David S, Seeber, Frank
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500979/
https://ncbi.nlm.nih.gov/pubmed/16778769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601189
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