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An 8 nt RNA triggers a rate-limiting shift of RNA polymerase II complexes into elongation

To better understand the critical conversions that RNA polymerase II complexes undergo during promoter escape, we determined in vitro the precise positions of the rate-limiting step and the last step requiring negative superhelicity or TFIIE and TFIIH. We found that both steps occur after synthesis...

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Detalhes bibliográficos
Main Authors: Hieb, Aaron R, Baran, Sean, Goodrich, James A, Kugel, Jennifer F
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500975/
https://ncbi.nlm.nih.gov/pubmed/16778763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601197
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