Llwytho...

Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element

MnmE, a Guanine nucleotide-binding protein conserved between bacteria and man, is involved in the modification of tRNAs. Here we provide biochemical and X-ray structural evidence for a new GTP-hydrolysis mechanism, where the G-domains of MnmE dimerise in a potassium-dependent manner and induce GTP h...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Scrima, Andrea, Wittinghofer, Alfred
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500855/
https://ncbi.nlm.nih.gov/pubmed/16763562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601171
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