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Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms

The crescent-shaped BAR (Bin/Amphiphysin/Rvs-homology) domain dimer is a versatile protein module that senses and generates positive membrane curvature. The BAR domain dimer of human endophilin-A1, solved at 3.1 Å, has a unique structure consisting of a pair of helix–loop appendages sprouting out fr...

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Detalhes bibliográficos
Main Authors: Masuda, Michitaka, Takeda, Soichi, Sone, Manami, Ohki, Takashi, Mori, Hidezo, Kamioka, Yuji, Mochizuki, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500852/
https://ncbi.nlm.nih.gov/pubmed/16763557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601176
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