Designed to be stable: Crystal structure of a consensus ankyrin repeat protein
Ankyrin repeat (AR) proteins mediate innumerable protein–protein interactions in virtually all phyla. This finding suggested the use of AR proteins as designed binding molecules. Based on sequence and structural analyses, we designed a consensus AR with fixed framework and randomized interacting res...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149896/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12566564/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0337680100 |
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