Flexible lid to the p53-binding domain of human Mdm2: Implications for p53 regulation
The stabilization of p53 against Mdm2-mediated degradation is an important event in DNA damage response. Initial models of p53 stabilization focused on posttranslational modification of p53 that would disrupt the p53–Mdm2 interaction. The N-terminal regions of both p53 and Mdm2 are modified in vivo...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149886/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12552135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0334477100 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|