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Inhibition of herpes simplex virus 1 gene expression by designer zinc-finger transcription factors
The herpes simplex virus 1 (HSV-1) replicative cycle begins by binding of the viral activator, VP16, to a set of sequences in the immediate-early (IE) gene promoters. With the aim of inhibiting this cycle, we have constructed a number of synthetic zinc-finger DNA-binding peptides by using recently r...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149882/ https://ncbi.nlm.nih.gov/pubmed/12574501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252773399 |
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