Inhibition of herpes simplex virus 1 gene expression by designer zinc-finger transcription factors

The herpes simplex virus 1 (HSV-1) replicative cycle begins by binding of the viral activator, VP16, to a set of sequences in the immediate-early (IE) gene promoters. With the aim of inhibiting this cycle, we have constructed a number of synthetic zinc-finger DNA-binding peptides by using recently r...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Papworth, Monika, Moore, Michael, Isalan, Mark, Minczuk, Michal, Choo, Yen, Klug, Aaron
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 2003
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149882/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12574501/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.252773399
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