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The RNA-binding Protein HuD Is Required for GAP-43 mRNA Stability, GAP-43 Gene Expression, and PKC-dependent Neurite Outgrowth in PC12 Cells

The RNA-binding protein HuD binds to a regulatory element in the 3′ untranslated region (3′ UTR) of the GAP-43 mRNA. To investigate the functional significance of this interaction, we generated PC12 cell lines in which HuD levels were controlled by transfection with either antisense (pDuH) or sense...

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Xehetasun bibliografikoak
Egile Nagusiak: Mobarak, Charlotte D., Anderson, Kim D., Morin, Melissa, Beckel-Mitchener, Andrea, Rogers, Sherry L., Furneaux, Henry, King, Peter, Perrone-Bizzozero, Nora I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2000
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Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC14985/
https://ncbi.nlm.nih.gov/pubmed/10982410
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