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De novo production of diverse intracellular antibody libraries

Many therapeutic targets are intracellular proteins and molecules designed to interact with them must effectively bind to their target inside the cell. Intracellular antibodies (intrabodies) recognise and bind to proteins in cells and various methods have been developed to produce such molecules. In...

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Main Authors: Tanaka, Tomoyuki, Chung, Grace T. Y., Forster, Alan, Lobato, M. Natividad, Rabbitts, Terence H.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC149845/
https://ncbi.nlm.nih.gov/pubmed/12595572
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