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De novo production of diverse intracellular antibody libraries

Many therapeutic targets are intracellular proteins and molecules designed to interact with them must effectively bind to their target inside the cell. Intracellular antibodies (intrabodies) recognise and bind to proteins in cells and various methods have been developed to produce such molecules. In...

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Auteurs principaux: Tanaka, Tomoyuki, Chung, Grace T. Y., Forster, Alan, Lobato, M. Natividad, Rabbitts, Terence H.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC149845/
https://ncbi.nlm.nih.gov/pubmed/12595572
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