Furin Processing and Proteolytic Activation of Semliki Forest Virus

The alphavirus Semliki Forest virus (SFV) infects cells via a low-pH-dependent membrane fusion reaction mediated by the E1 envelope protein. Fusion is regulated by the interaction of E1 with the receptor-binding protein E2. E2 is synthesized as a precursor termed “p62,” which forms a stable heterodi...

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Bibliographic Details
Main Authors: Zhang, Xinyong, Fugère, Martin, Day, Robert, Kielian, Margaret
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC149766/
https://ncbi.nlm.nih.gov/pubmed/12584323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.5.2981-2989.2003
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