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Simian-Human Immunodeficiency Virus SHIV89.6-Induced Protection against Intravaginal Challenge with Pathogenic SIVmac239 Is Independent of the Route of Immunization and Is Associated with a Combination of Cytotoxic T-Lymphocyte and Alpha Interferon Responses

Attenuated primate lentivirus vaccines provide the most consistent protection against challenge with pathogenic simian immunodeficiency virus (SIV). Thus, they provide an excellent model to examine the influence of the route of immunization on challenge outcome and to study vaccine-induced protectiv...

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Main Authors: Abel, Kristina, Compton, Lara, Rourke, Tracy, Montefiori, David, Lu, Ding, Rothaeusler, Kristina, Fritts, Linda, Bost, Kristen, Miller, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC149756/
https://ncbi.nlm.nih.gov/pubmed/12584336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.5.3099-3118.2003
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