Evaluation of Genetically Engineered Derivatives of a Chinese Strain of Foot-and-Mouth Disease Virus Reveals a Novel Cell-Binding Site Which Functions in Cell Culture and in Animals

Adaptation of field isolates of foot-and-mouth disease virus (FMDV) to grow in cells in culture can result in changes in viral properties that include acquisition of the ability to bind to cell surface heparan sulfate (HS). After 13 passages on BHK cells to produce a vaccine, a Cathay topotype isola...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Zhao, Qizu, Pacheco, Juan M., Mason, Peter W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Recombination and Evolution
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12584350/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.5.3269-3280.2003
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