Presence of Replicating Virus in Recombinant Hepadnavirus Stocks Results from Recombination and Can Be Eliminated by the Use of a Packaging Cell Line

Mutant hepatitis B viruses are useful tools to study the viral life cycle and viral pathogenesis. Furthermore, recombinant hepatitis B viruses are candidate vectors for liver-directed gene therapy. Because wild-type viruses present in recombinant or mutant virus stocks may falsify experimental resul...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Klöcker, Uta, Oberwinkler, Heike, Kürschner, Timo, Protzer, Ulrike
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Recombination and Evolution
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12584311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.5.2873-2881.2003
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