Effects of Dipeptide Insertions between Codons 69 and 70 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase on Primer Unblocking, Deoxynucleoside Triphosphate Inhibition, and DNA Chain Elongation

Finger insertion mutations of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) (T69S mutations followed by various dipeptide insertions) have a multinucleoside resistance phenotype that can be explained by decreased sensitivity to deoxynucleoside triphosphate (dNTP) inhibition...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Meyer, Peter R., Lennerstrand, Johan, Matsuura, Suzanne E., Larder, Brendan A., Scott, Walter A.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2003
Assuntos:	Vaccines and Antiviral Agents
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149510/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12610164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.6.3871-3877.2003
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