Neurovirulence in Mice of H5N1 Influenza Virus Genotypes Isolated from Hong Kong Poultry in 2001

We studied the pathogenicity of five different genotypes (A to E) of highly pathogenic avian H5N1 viruses, which contained HA genes similar to those of the H5N1 virus A/goose/Guangdong/1/96 and five different combinations of “internal” genes, in a mouse model. Highly pathogenic, neurotropic variants...

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Detalhes bibliográficos
Main Authors: Lipatov, Aleksandr S., Krauss, Scott, Guan, Yi, Peiris, Malik, Rehg, Jerold E., Perez, Daniel R., Webster, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149508/
https://ncbi.nlm.nih.gov/pubmed/12610156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.6.3816-3823.2003
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