Neurovirulence in Mice of H5N1 Influenza Virus Genotypes Isolated from Hong Kong Poultry in 2001

We studied the pathogenicity of five different genotypes (A to E) of highly pathogenic avian H5N1 viruses, which contained HA genes similar to those of the H5N1 virus A/goose/Guangdong/1/96 and five different combinations of “internal” genes, in a mouse model. Highly pathogenic, neurotropic variants...

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Bibliographische Detailangaben
Hauptverfasser: Lipatov, Aleksandr S., Krauss, Scott, Guan, Yi, Peiris, Malik, Rehg, Jerold E., Perez, Daniel R., Webster, Robert G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149508/
https://ncbi.nlm.nih.gov/pubmed/12610156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.6.3816-3823.2003
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