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Rational Site-Directed Mutations of the LLP-1 and LLP-2 Lentivirus Lytic Peptide Domains in the Intracytoplasmic Tail of Human Immunodeficiency Virus Type 1 gp41 Indicate Common Functions in Cell-Cell Fusion but Distinct Roles in Virion Envelope Incorporation

Two highly conserved cationic amphipathic α-helical motifs, designated lentivirus lytic peptides 1 and 2 (LLP-1 and LLP-2), have been characterized in the carboxyl terminus of the transmembrane (TM) envelope glycoprotein (Env) of lentiviruses . Although various properties have been attributed to the...

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Bibliografske podrobnosti
Main Authors: Kalia, Vandana, Sarkar, Surojit, Gupta, Phalguni, Montelaro, Ronald C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC149489/
https://ncbi.nlm.nih.gov/pubmed/12610139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.6.3634-3646.2003
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