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Electrostatic Modulation in Steroid Receptor Recruitment of LXXLL and FXXLF Motifs

Coactivator recruitment by activation function 2 (AF2) in the steroid receptor ligand binding domain takes place through binding of an LXXLL amphipathic α-helical motif at the AF2 hydrophobic surface. The androgen receptor (AR) and certain AR coregulators are distinguished by an FXXLF motif that int...

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Udgivet i:Mol Cell Biol
Principais autores: He, Bin, Wilson, Elizabeth M.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149467/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12612084/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.6.2135-2150.2003
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