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MHC class I expression protects rat colon carcinoma cells from hepatic natural killer cell-mediated apoptosis and cytolysis, by blocking the perforin/granzyme pathway

BACKGROUND: Hepatic natural killer (NK) cells, the most cytotoxic cells of the natural occurring NK cells, are located in the liver sinusoids and are thus in a strategic position to kill arriving metastasising tumour cells, like colon carcinoma cells. It is known that major histocompatibility comple...

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מידע ביבליוגרפי
Main Authors: Luo, Dianzhong, Vermijlen, David, Kuppen, Peter JK, Wisse, Eddie
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2002
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC149428/
https://ncbi.nlm.nih.gov/pubmed/12495445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-5926-1-2
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