MHC class I expression protects rat colon carcinoma cells from hepatic natural killer cell-mediated apoptosis and cytolysis, by blocking the perforin/granzyme pathway

BACKGROUND: Hepatic natural killer (NK) cells, the most cytotoxic cells of the natural occurring NK cells, are located in the liver sinusoids and are thus in a strategic position to kill arriving metastasising tumour cells, like colon carcinoma cells. It is known that major histocompatibility comple...

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Detalles Bibliográficos

Publicado en:	Comp Hepatol
Principais autores:	Luo, Dianzhong, Vermijlen, David, Kuppen, Peter JK, Wisse, Eddie
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2002
Assuntos:	Research
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149428/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12495445/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1476-5926-1-2
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