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MHC class I expression protects rat colon carcinoma cells from hepatic natural killer cell-mediated apoptosis and cytolysis, by blocking the perforin/granzyme pathway
BACKGROUND: Hepatic natural killer (NK) cells, the most cytotoxic cells of the natural occurring NK cells, are located in the liver sinusoids and are thus in a strategic position to kill arriving metastasising tumour cells, like colon carcinoma cells. It is known that major histocompatibility comple...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149428/ https://ncbi.nlm.nih.gov/pubmed/12495445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-5926-1-2 |
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