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Ancient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteins

BACKGROUND: Soluble guanylyl cyclases (SGCs) are dimeric enzymes that transduce signals downstream of nitric oxide (NO) in animals. They sense NO by means of a heme moiety that is bound to their N-terminal extensions. RESULTS: Using sequence profile searches we show that the N-terminal extensions of...

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Autors principals: Iyer, Lakshminarayan M, Anantharaman, Vivek, Aravind, L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC149354/
https://ncbi.nlm.nih.gov/pubmed/12590654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-4-5
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